Annotation Detail
Information
- Associated Genes
- EGFR
- Associated Variants
-
EGFR p.Leu858Arg (p.L858R)
(
ENST00000275493.7,
ENST00000450046.2,
ENST00000455089.5 )
EGFR p.Leu858Arg (p.L858R) ( ENST00000275493.7, ENST00000450046.2, ENST00000455089.5 ) - Associated Disease
- Adenocarcinoma of lung (disorder)
- Source Database
- DisGeNET
- Description
- A total of 169 cases (78 biopsies and 91 resected specimens) of lung adenocarcinoma with EGFR mutation status predefined by direct DNA sequencing were histologically examined, and IHC was performed using EGFR mutation-specific antibodies of del E746-A750 and L858R.
- Pubmed
- 23465272
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.2
- Year of publication
- 2013
Drugs