Annotation Detail

Information
Associated Genes
EGFR
Associated Variants
EGFR p.Leu858Arg (p.L858R) ( ENST00000275493.7, ENST00000450046.2, ENST00000455089.5 )
EGFR p.Leu858Arg (p.L858R) ( ENST00000275493.7, ENST00000450046.2, ENST00000455089.5 )
Associated Disease
Malignant neoplasm of lung
Source Database
DisGeNET
Description
Next, we examined the role of RhoB in lung cancer progression in transgenic mice that express inducible EGFR(L858R) crossed with Rhob null mice.
Pubmed
25320360
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.16
Year of publication
2015
Drugs