Annotation Detail

Information
Associated Genes
ALK
Associated Variants
EGFR p.Leu858Arg (p.L858R) ( ENST00000275493.7, ENST00000450046.2, ENST00000455089.5 )
EGFR p.Leu858Arg (p.L858R) ( ENST00000275493.7, ENST00000450046.2, ENST00000455089.5 )
Associated Disease
adenocarcinoma
Source Database
DisGeNET
Description
We report here a case of pulmonary adenocarcinoma with concomitant EGFR mutation in exon 21 (L858R) and ALK rearrangement in naive and relapsed tumors.
Pubmed
25312989
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0338642206615814
Year of publication
2014
Drugs