Annotation Detail

Information
Associated Genes
EGFR
Associated Variants
EGFR p.Leu858Arg (p.L858R) ( ENST00000275493.7, ENST00000450046.2, ENST00000455089.5 )
EGFR p.Leu858Arg (p.L858R) ( ENST00000275493.7, ENST00000450046.2, ENST00000455089.5 )
Associated Disease
Adenocarcinoma of lung (disorder)
Source Database
DisGeNET
Description
The present study describes a case of a 60-year-old Japanese man who was histologically diagnosed with lung adenocarcinoma harboring L858R mutation of epidermal growth factor receptor.
Pubmed
22185996
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.2
Year of publication
2011
Drugs