Annotation Detail
Information
- Associated Genes
- CRHR1
- Associated Variants
-
CRHR1 MUTATION
CRHR1 MUTATION - Associated Disease
- Mental Depression
- Source Database
- DisGeNET
- Description
- Previous research supports gene-environment interactions for polymorphisms in the corticotropin hormone receptor 1 gene (CRHR1) and the serotonin transporter gene linked polymorphic region (5-HTTLPR) in predicting depression, but it has rarely considered genetic influences on stress sensitization processes, whereby early adversities (EA) increase depressive reactivity to proximal stressors later in life.
- Pubmed
- 25422958
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 1
- Original source reporting the Gene Disease association
- BeFree,GAD
- DisGENET score for the Gene Disease association
- 0.0204453549294592
Drugs