Annotation Detail

Information
Associated Genes
PKP2
Associated Variants
PKP2 p.Arg735Ter (p.R735*) ( ENST00000340811.9, ENST00000070846.11, ENST00000549461.3, ENST00000700558.2, ENST00000700559.2 )
PKP2 p.Arg735Ter (p.R735*) ( ENST00000070846.11, ENST00000340811.9, ENST00000549461.3, ENST00000700558.2, ENST00000700559.2 )
Associated Disease
Arrhythmogenic Right Ventricular Dysplasia
Source Database
DisGeNET
Description
The introduction of the PKP2 R735X mutation into mice resulted in an exercise-dependent ARVC phenotype.
Pubmed
25857910
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.163220184922405
Year of publication
2015
Drugs