Annotation Detail

Information
Associated Genes
CSK
Associated Variants
CYP17A1 c.666+35T>C ( ENST00000638272.1, ENST00000369887.4, ENST00000638971.1, ENST00000638190.1, ENST00000639393.1 )
ATP2B1 c.-221-10702C>T ( ENST00000551310.2, ENST00000705822.1, ENST00000428670.8, ENST00000359142.8 )
CSK c.-66+2306C>A ( ENST00000439220.6, ENST00000220003.14 )
MTHFR p.Ala263Val (p.A263V) ( ENST00000376585.6, ENST00000376583.7, ENST00000376590.9, ENST00000376592.6, ENST00000423400.7, ENST00000641407.1, ENST00000641820.1 )
STK39 c.628+2383G>A ( ENST00000355999.5, ENST00000697205.1 )
rs16998073
CYP17A1 c.666+35T>C ( ENST00000369887.4, ENST00000638190.1, ENST00000638272.1, ENST00000638971.1, ENST00000639393.1 )
ATP2B1 c.-221-10702C>T ( ENST00000359142.8, ENST00000428670.8, ENST00000551310.2, ENST00000705822.1 )
CSK c.-66+2306C>A ( ENST00000220003.14, ENST00000439220.6 )
MTHFR p.Ala263Val (p.A263V) ( ENST00000376583.7, ENST00000376585.6, ENST00000376590.9, ENST00000376592.6, ENST00000423400.7, ENST00000641407.1, ENST00000641820.1 )
STK39 c.628+2383G>A ( ENST00000355999.5, ENST00000697205.1 )
rs16998073
Associated Disease
Hypertensive disease
Source Database
DisGeNET
Description
The present study confirmed the significant association of ATP2B1 rs17249754 with risk of hypertension among Chinese children, but failed to replicate the association of CSK rs1378942, MTHFR rs1801133, CYP17A1 rs1004467, STK39 rs3754777 and FGF5 rs16998073 with BP/risk of hypertension.
Pubmed
23759979
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0116396628910506
Year of publication
2013
Drugs