Annotation Detail

Information
Associated Genes
HMCN1
Associated Variants
HMCN1 p.Gln5345Arg (p.Q5345R) ( ENST00000271588.9 )
HMCN1 p.Gln5345Arg (p.Q5345R) ( ENST00000271588.9 )
Associated Disease
age related macular degeneration
Source Database
DisGeNET
Description
The A16,263G mutation in the HEMICENTIN-1 gene produces a non-conservative substitution of arginine for glutamine at codon 5345 which has been implicated in familial AMD.
Pubmed
15467524
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0164358590216495
Year of publication
2004
Drugs