Annotation Detail

Information
Associated Genes
AIRE
Associated Variants
AIRE p.Arg139Gly (p.R139G) ( ENST00000291582.6 )
AIRE p.Arg139Ter (p.R139*) ( ENST00000291582.6 )
AIRE p.Arg139Gly (p.R139G) ( ENST00000291582.6 )
AIRE p.Arg139Ter (p.R139*) ( ENST00000291582.6 )
Associated Disease
Autoimmune Diseases
Source Database
DisGeNET
Description
Given the carrier frequency of R139X in the Sardinian population, AIRE may be implicated in the pathogenesis of other autoimmune diseases in the Sardinian population, particularly those affecting the endocrine system.
Pubmed
9856486
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0226690905578324
Year of publication
1998
Drugs