Annotation Detail

Information
Associated Genes
IRF6
Associated Variants
ENSG00000289700 p.Pro396Ser (p.P396S), IRF6 p.Pro396Ser (p.P396S) ( ENST00000542854.5, ENST00000367021.8 )
ENSG00000289700 p.Arg45Gln (p.R45Q), IRF6 p.Arg45Gln (p.R45Q) ( ENST00000367021.8, ENST00000542854.5 )
ENSG00000289700 p.Pro396Ser (p.P396S), IRF6 p.Pro396Ser (p.P396S) ( ENST00000367021.8, ENST00000542854.5 )
ENSG00000289700 p.Arg45Gln (p.R45Q), IRF6 p.Arg45Gln (p.R45Q) ( ENST00000367021.8, ENST00000542854.5 )
Associated Disease
Van der Woude syndrome
Source Database
DisGeNET
Description
Novel IRF6 mutations in Japanese patients with Van der Woude syndrome: two missense mutations (R45Q and P396S) and a 17-kb deletion.
Pubmed
14618417
Original source reporting the Gene Disease association
UNIPROT
DisGENET score for the Gene Disease association
0.575396241838457
Year of publication
2003
Drugs