Annotation Detail

Information
Associated Genes
NGFR
Associated Variants
BDNF c.*2327G>A ( ENST00000356660.9, ENST00000314915.6, ENST00000395981.7, ENST00000532997.5, ENST00000530861.5, ENST00000439476.6, ENST00000533246.5, ENST00000525950.5, ENST00000418212.5, ENST00000395983.7, ENST00000395986.6, ENST00000438929.5, ENST00000525528.1, ENST00000533131.5, ENST00000395978.7 )
NGFR c.67-1307T>C ( ENST00000504201.1, ENST00000172229.8 )
NGFR p.Ser205Leu (p.S205L) ( ENST00000504201.1, ENST00000172229.8 )
FYN c.1405+36T>C ( ENST00000229471.8, ENST00000354650.7, ENST00000368667.6, ENST00000368678.8, ENST00000368682.8 )
rs1212171
BDNF c.*2327G>A ( ENST00000314915.6, ENST00000356660.9, ENST00000395978.7, ENST00000395981.7, ENST00000395983.7, ENST00000395986.6, ENST00000418212.5, ENST00000438929.5, ENST00000439476.6, ENST00000525528.1, ENST00000525950.5, ENST00000530861.5, ENST00000532997.5, ENST00000533131.5, ENST00000533246.5 )
NGFR c.67-1307T>C ( ENST00000172229.8, ENST00000504201.1 )
NGFR p.Ser205Leu (p.S205L) ( ENST00000172229.8, ENST00000504201.1 )
FYN c.1405+36T>C ( ENST00000229471.8, ENST00000354650.7, ENST00000368667.6, ENST00000368678.8, ENST00000368682.8 )
rs1212171
Associated Disease
asthma
Source Database
DisGeNET
Description
Analysis stratified by asthma-related phenotype revealed an association between atopy and NGFR (rs3785931), while BDNF (rs7124442), NTRK2 (rs1212171), NGFR (rs2072446), and FYN (rs3730353) variants were associated with increased exhaled nitric oxide (exNO).
Pubmed
22468730
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00263847385068233
Year of publication
2012
Drugs