Annotation Detail
Information
- Associated Genes
- IL6R
- Associated Variants
-
IL6R c.85+2913A>G
(
ENST00000622330.5,
ENST00000368485.8,
ENST00000344086.8 )
IL6R p.Asp358Ala (p.D358A) ( ENST00000368485.8, ENST00000344086.8 )
IL6R p.Asp358Val (p.D358V) ( ENST00000368485.8, ENST00000344086.8 )
IL6R c.1161-5190T>C ( ENST00000368485.8, ENST00000344086.8 )
IL6R c.85+2913A>G ( ENST00000344086.8, ENST00000368485.8, ENST00000622330.5 )
IL6R p.Asp358Ala (p.D358A) ( ENST00000344086.8, ENST00000368485.8 )
IL6R p.Asp358Val (p.D358V) ( ENST00000344086.8, ENST00000368485.8 )
IL6R c.1161-5190T>C ( ENST00000344086.8, ENST00000368485.8 ) - Associated Disease
- rheumatoid arthritis
- Source Database
- DisGeNET
- Description
- Interleukin-6-receptor polymorphisms rs12083537, rs2228145, and rs4329505 as predictors of response to tocilizumab in rheumatoid arthritis.
- Pubmed
- 24978393
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.247719924550087
- Year of publication
- 2014
Drugs