Annotation Detail

Information
Associated Genes
KCNQ1
Associated Variants
KCNQ1 p.Gly269Ser (p.G269S) ( ENST00000335475.6, ENST00000496887.7, ENST00000155840.12, ENST00000646564.2, ENST00000713725.1 )
KCNQ1 p.Gly269Arg (p.G269R) ( ENST00000496887.7, ENST00000155840.12, ENST00000335475.6, ENST00000646564.2, ENST00000713725.1 )
KCNQ1 p.Gly269Ser (p.G269S) ( ENST00000155840.12, ENST00000335475.6, ENST00000496887.7, ENST00000646564.2, ENST00000713725.1 )
KCNQ1 p.Gly269Arg (p.G269R) ( ENST00000155840.12, ENST00000335475.6, ENST00000496887.7, ENST00000646564.2, ENST00000713725.1 )
Associated Disease
Syncope
Source Database
DisGeNET
Description
Although G269S in the KVLQT1 gene was detected in a female with known family history of syncope and sudden cardiac death, no other mutations were found in any of the 14 cases, and no other mutations was found in 200 controls.
Pubmed
16436635
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00962001765464952
Year of publication
2006
Drugs