Annotation Detail

Information
Associated Genes
FGFR3
Associated Variants
FGFR3 MUTATION
FGFR3 MUTATION
Associated Disease
craniosynostosis
Source Database
DisGeNET
Description
Most reported mutations in the FGFR3 gene are dominant activating mutations that cause a variety of short-limbed bone dysplasias including achondroplasia and syndromic craniosynostosis.
Pubmed
24864036
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree,GAD,LHGDN
DisGENET score for the Gene Disease association
0.0301275047575036
Drugs