Annotation Detail

Information
Associated Genes
AGTR1
Associated Variants
AGTR1 MUTATION
AGTR1 MUTATION
Associated Disease
Coronary heart disease
Source Database
DisGeNET
Description
Our study intended to prove whether agonistic autoantibodies to angiotensin II type 1 receptor (AT1-AAs) exist in patients with coronary heart disease (CHD) and affect the human endothelial cell (HEC) by upregulating proinflammatory cytokines expression involved in NF-κB pathway.
Pubmed
25762441
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree,GAD,LHGDN
DisGENET score for the Gene Disease association
0.0388149827957249
Drugs