Annotation Detail

Information
Associated Genes
ABCG5
Associated Variants
ABCG5 p.Gln604Glu (p.Q604E) ( ENST00000405322.8 )
ABCG8 p.Asp19Asn (p.D19N) ( ENST00000272286.4 )
ABCG8 p.Asp19His (p.D19H) ( ENST00000272286.4 )
ABCG5 p.Gln604Glu (p.Q604E) ( ENST00000405322.8 )
ABCG8 p.Asp19Asn (p.D19N) ( ENST00000272286.4 )
ABCG8 p.Asp19His (p.D19H) ( ENST00000272286.4 )
Associated Disease
cholelithiasis
Source Database
DisGeNET
Description
Recently, variants of the hepatocanalicular cholesterol hemitransporters ABCG5/8 were linked to gallstone disease; ABCG8 D19H in Caucasians and ABCG5 Q604E in Chinese.
Pubmed
20497293
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.132453988507291
Year of publication
2010
Drugs