Annotation Detail
Information
- Associated Genes
- IFNL3
- Associated Variants
-
IFNL3 c.271-126T>C
(
ENST00000413851.3,
ENST00000613087.5 )
IFNL3 p.Lys74Arg (p.K74R) ( ENST00000413851.3, ENST00000613087.5 )
IFNL4 c.151-152G>A ( ENST00000606380.2 )
NC_000019.10:g.39252525T>G
IFNL3 c.271-126T>C ( ENST00000413851.3, ENST00000613087.5 )
IFNL3 p.Lys74Arg (p.K74R) ( ENST00000413851.3, ENST00000613087.5 )
IFNL4 c.151-152G>A ( ENST00000606380.2 )
NC_000019.10:g.39252525T>G - Associated Disease
- hepatitis C
- Source Database
- DisGeNET
- Description
- This study demonstrated that Indonesian patients with chronic hepatitis C (mostly ethnic Java people) mostly were infected with hepatitis C virus (HCV) genotype 1; however, they carried mainly the major genotypes of interleukin 28B (IL-28B) single nucleotide polymorphisms (SNPs) (rs12979860 CC, rs11881222 TT, rs8103142 AA, and rs8099917 TT), and they mostly achieved sustained virological responses to pegylated interferon/ribavirin treatment.
- Pubmed
- 24696021
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.220488369584746
- Year of publication
- 2015
Drugs