Annotation Detail
Information
- Associated Genes
- RAF1
- Associated Variants
-
RAF1 MUTATION
RAF1 MUTATION - Associated Disease
- Colorectal Neoplasms
- Source Database
- DisGeNET
- Description
- Preclinical data show that reactivation of EGFR signaling occurs in colorectal tumor cells treated with RAF inhibitors and that the addition of an EGFR inhibitor enhances antitumor activity.
- Pubmed
- 25589621
- Section of the abstract supporting the evidence
- PURPOSE
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 2
- Original source reporting the Gene Disease association
- BeFree,LHGDN
- DisGENET score for the Gene Disease association
- 0.00353867585870808
Drugs