Annotation Detail
Information
- Associated Genes
- HTR3B
- Associated Variants
-
HTR3B p.Tyr129Ser (p.Y129S)
(
ENST00000537778.5,
ENST00000260191.8 )
HTR3B p.Tyr129Ser (p.Y129S) ( ENST00000260191.8, ENST00000537778.5 ) - Associated Disease
- Alcoholic Intoxication, Chronic
- Source Database
- DisGeNET
- Description
- The HTR3B rs1176744 gain-of-function Ser129 allele predicted alcohol dependence (P=0.002) and low 5-HTTLPR activity predicted cocaine/heroin dependence (P=0.01).
- Pubmed
- 20838391
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00318135759484294
- Year of publication
- 2011
Drugs