Annotation Detail
Information
- Associated Genes
- SLC30A8
- Associated Variants
-
ADCY5 c.1406+851T>C
(
ENST00000309879.9,
ENST00000462833.6,
ENST00000466617.6,
ENST00000470367.2,
ENST00000483566.2,
ENST00000491190.5,
ENST00000699714.1,
ENST00000699715.1,
ENST00000699716.1,
ENST00000699718.1 )
GLIS3 c.-98-2527G>T ( ENST00000381971.8, ENST00000682749.1 )
ADCY5 c.1406+851T>C ( ENST00000309879.9, ENST00000462833.6, ENST00000466617.6, ENST00000470367.2, ENST00000483566.2, ENST00000491190.5, ENST00000699714.1, ENST00000699715.1, ENST00000699716.1, ENST00000699718.1 )
GLIS3 c.-98-2527G>T ( ENST00000381971.8, ENST00000682749.1 ) - Associated Disease
- Diabetes Mellitus, Non-Insulin-Dependent
- Source Database
- DisGeNET
- Description
- In addition to previously reported type 2 diabetes risk variants in TCF7L2 and SLC30A8, SNPs in ADCY5 (rs11708067) and GLIS3 (rs7034200) displayed evidence for association with type 2 diabetes, with odds ratios of 1.23 (95% CI: 1.09, 1.39; p = 9.1×10(-4)) and 1.16 (95% CI: 1.05, 1.29; p = 3.49×10(-3)) respectively.
- Pubmed
- 21949744
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.339815256661862
- Year of publication
- 2011
Drugs