Annotation Detail

Information
Associated Genes
HNF1A
Associated Variants
HNF1A p.Ile27Leu (p.I27L) ( ENST00000541395.5, ENST00000257555.11, ENST00000400024.6, ENST00000544413.2 )
HNF1A p.Ser487Asn (p.S487N) ( ENST00000544413.2, ENST00000541395.5, ENST00000257555.11, ENST00000400024.6 )
HNF1A p.Ile27Leu (p.I27L) ( ENST00000257555.11, ENST00000400024.6, ENST00000541395.5, ENST00000544413.2 )
HNF1A p.Ser487Asn (p.S487N) ( ENST00000257555.11, ENST00000400024.6, ENST00000541395.5, ENST00000544413.2 )
Associated Disease
Coronary Arteriosclerosis
Source Database
DisGeNET
Description
The HNF1A Ser486Asn and/or Ile27Leu variants were also associated with increased risk of subclinical coronary atherosclerosis in Coronary Artery Risk Development in Young Adults and with incident coronary heart disease in Cardiovascular Health Study.
Pubmed
20031592
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00135720936040152
Year of publication
2009
Drugs