Annotation Detail
Information
- Associated Genes
- PPARG
- Associated Variants
-
PPARG MUTATION
PPARG MUTATION - Associated Disease
- colitis
- Source Database
- DisGeNET
- Description
- Altogether these data demonstrate that PAK1 overexpression and activation in inflammation and colitis-associated cancer promote NF-κB activity via suppression of PPARγ in intestinal epithelial cells.
- Pubmed
- 26036343
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 13
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00190009310456212
Drugs