Annotation Detail
Information
- Associated Genes
- CHRNA3
- Associated Variants
-
CHRNA5 c.259-1837A>G
(
ENST00000299565.9,
ENST00000559554.5 )
CHRNA5 c.414-529T>C ( ENST00000559554.5, ENST00000299565.9 )
CHRNA5 p.Asp398Asn (p.D398N) ( ENST00000299565.9, ENST00000559554.5 )
CHRNA3 c.*546C>T ( ENST00000348639.7, ENST00000326828.6 )
CHRNA5 c.259-1837A>G ( ENST00000299565.9, ENST00000559554.5 )
CHRNA5 c.414-529T>C ( ENST00000299565.9, ENST00000559554.5 )
CHRNA5 p.Asp398Asn (p.D398N) ( ENST00000299565.9, ENST00000559554.5 )
CHRNA3 c.*546C>T ( ENST00000326828.6, ENST00000348639.7 ) - Associated Disease
- Malignant neoplasm of lung
- Source Database
- DisGeNET
- Description
- A four-SNP haplotype spanning CHRNA5 (rs11637635 C, rs17408276 T, rs16969968 G) and CHRNA3 (rs578776 G) was associated with increased lung cancer risk (P = 0.002).
- Pubmed
- 20587604
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.179208137073453
- Year of publication
- 2010
Drugs