Annotation Detail
Information
- Associated Genes
- SF3B2
- Associated Variants
-
SF3B2 MUTATION
SF3B2 MUTATION - Associated Disease
- Congenital chromosomal disease
- Source Database
- DisGeNET
- Description
- The expression of unmutated immunoglobulin heavy chain variable region (IGHV) genes, ZAP-70 and CD38 proteins, the occurrence of chromosomal abnormalities such as 17p and 11q deletions and mutations of the NOTCH1, SF3B1 and BIRC3 genes have been associated with a poor prognosis.
- Pubmed
- 25563586
- Section of the abstract supporting the evidence
- RESULTS
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs