Annotation Detail

Information
Associated Genes
IDH2
Associated Variants
IDH2 MUTATION
IDH2 MUTATION
Associated Disease
chondroblastoma
Source Database
DisGeNET
Description
Specific H3F3A driver mutations and IDH2 mutations were recently described in giant cell tumor of bone (GCTB) and H3F3B driver mutations in chondroblastoma; these may be helpful as a diagnostic tool for giant cell-containing tumors of the bone.
Pubmed
26457357
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs