Annotation Detail
Information
- Associated Genes
- IL2RA
- Associated Variants
-
IL2RA c.64+5006A>G
(
ENST00000256876.10,
ENST00000447847.2,
ENST00000697424.1,
ENST00000379959.8,
ENST00000379954.5 )
NC_000010.11:g.6072697C>A
NC_000010.11:g.6080046T>A
IL2RA c.64+5006A>G ( ENST00000256876.10, ENST00000379954.5, ENST00000379959.8, ENST00000447847.2, ENST00000697424.1 )
NC_000010.11:g.6072697C>A
NC_000010.11:g.6080046T>A - Associated Disease
- multiple sclerosis
- Source Database
- DisGeNET
- Description
- Using a cohort of over 700 AAV patients, two SLE case-control studies and an SLE trio collection (totalling over 1000 SLE patients), and a TaqMan genotyping approach, we tested 3 SNPs in the IL2RA locus, rs11594656, rs2104286 & rs41295061, each with a prior association with autoimmune disease; rs11594656 and rs41295061 with type 1 diabetes (T1D) and rs2104286 with multiple sclerosis (MS) and T1D.
- Pubmed
- 19265545
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.303190007587811
- Year of publication
- 2009
Drugs