Annotation Detail

Information
Associated Genes
KCNJ11
Associated Variants
KCNJ11 p.Val64Leu (p.V64L) ( ENST00000528731.1, ENST00000682764.1, ENST00000682350.1, ENST00000339994.5 )
KCNJ11 p.Phe60Tyr (p.F60Y) ( ENST00000339994.5, ENST00000682350.1, ENST00000682764.1, ENST00000528731.1 )
KCNJ11 p.Val64Leu (p.V64L) ( ENST00000339994.5, ENST00000528731.1, ENST00000682350.1, ENST00000682764.1 )
KCNJ11 p.Phe60Tyr (p.F60Y) ( ENST00000339994.5, ENST00000528731.1, ENST00000682350.1, ENST00000682764.1 )
Associated Disease
epilepsy
Source Database
DisGeNET
Description
We report two novel mutations on the same haplotype (cis), F60Y and V64L, in the slide helix of Kir6.2 in a patient with neonatal diabetes, developmental delay and epilepsy.
Pubmed
20022885
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0103445857040439
Year of publication
2010
Drugs