Annotation Detail

Information
Associated Genes
CYP24A1
Associated Variants
VDR p.Ile352= (p.I352=) ( ENST00000229022.9, ENST00000550325.5, ENST00000549336.6, ENST00000395324.6 )
VDR c.1025-49G>T ( ENST00000550325.5, ENST00000549336.6, ENST00000395324.6, ENST00000229022.9 )
VDR c.1024+443G>A ( ENST00000550325.5, ENST00000395324.6, ENST00000549336.6, ENST00000229022.9 )
VDR c.277+3260C>T ( ENST00000395324.6, ENST00000549336.6, ENST00000550325.5, ENST00000229022.9 )
CYP27B1 c.1137-29T>C ( ENST00000228606.9, ENST00000713544.1, ENST00000713545.1, ENST00000546567.5 )
CYP24A1 c.*10+967A>G ( ENST00000216862.8, ENST00000395954.3, ENST00000395955.7 )
GC p.Asp451Glu (p.D451E) ( ENST00000273951.13, ENST00000504199.5, ENST00000513476.5 )
GC c.115+6190A>G ( ENST00000273951.13, ENST00000504199.5, ENST00000513476.5 )
VDR p.Ile352= (p.I352=) ( ENST00000229022.9, ENST00000395324.6, ENST00000549336.6, ENST00000550325.5 )
VDR c.1025-49G>T ( ENST00000229022.9, ENST00000395324.6, ENST00000549336.6, ENST00000550325.5 )
VDR c.1024+443G>A ( ENST00000229022.9, ENST00000395324.6, ENST00000549336.6, ENST00000550325.5 )
VDR c.277+3260C>T ( ENST00000229022.9, ENST00000395324.6, ENST00000549336.6, ENST00000550325.5 )
CYP27B1 c.1137-29T>C ( ENST00000228606.9, ENST00000546567.5, ENST00000713544.1, ENST00000713545.1 )
CYP24A1 c.*10+967A>G ( ENST00000216862.8, ENST00000395954.3, ENST00000395955.7 )
GC p.Asp451Glu (p.D451E) ( ENST00000273951.13, ENST00000504199.5, ENST00000513476.5 )
GC c.115+6190A>G ( ENST00000273951.13, ENST00000504199.5, ENST00000513476.5 )
Associated Disease
melanoma
Source Database
DisGeNET
Description
In our hospital-based case-control study including 305 melanoma patients and 370 healthy controls single nucleotide polymorphisms in the genes CYP27B1 (rs4646536), CYP24A1 (rs927650), VDBP (rs1155563, rs7041), and VDR (rs757343, rs731236, rs2107301, rs7975232) were analyzed for their association with melanoma risk and prognosis.
Pubmed
22576141
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00135720936040152
Year of publication
2012
Drugs