Annotation Detail

Information
Associated Genes
CDK4
Associated Variants
CDK4 p.Arg24Cys (p.R24C) ( ENST00000549606.5, ENST00000312990.10, ENST00000257904.11 )
CDK4 p.Arg24Cys (p.R24C) ( ENST00000257904.11, ENST00000312990.10, ENST00000549606.5 )
Associated Disease
Melanoma, cutaneous malignant, susceptibility to, 3
Source Database
DisGeNET
Description
Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma.
Pubmed
8528263
Original source reporting the Gene Disease association
UNIPROT
DisGENET score for the Gene Disease association
0.36
Year of publication
1996
Drugs