Annotation Detail

Information
Associated Genes
CDK4
Associated Variants
CDK4 p.Arg24Cys (p.R24C) ( ENST00000549606.5, ENST00000312990.10, ENST00000257904.11 )
CDK4 p.Arg24Cys (p.R24C) ( ENST00000257904.11, ENST00000312990.10, ENST00000549606.5 )
Associated Disease
melanoma
Source Database
DisGeNET
Description
Autochthonous primary and metastatic melanomas in Hgf-Cdk4 R24C mice evade T-cell-mediated immune surveillance.
Pubmed
20649939
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0614167218734491
Year of publication
2010
Drugs