Annotation Detail

Information
Associated Genes
TLR4
Associated Variants
rs2910164
ENSG00000285082 c.140+7124G>C, TLR4 c.*1205G>C ( ENST00000355622.8 )
rs2910164
ENSG00000285082 c.140+7124G>C, TLR4 c.*1205G>C ( ENST00000355622.8 )
Associated Disease
Malignant neoplasm of stomach
Source Database
DisGeNET
Description
This study aimed to examine the associations of the miR-146a G/C (rs2910164) and TLR4 +3725 G/C (rs11536889) polymorphisms with the risk of Helicobacter pylori (H. pylori) infection, gastric atrophy, and gastric cancer in a Japanese population.
Pubmed
20721625
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00888163690852931
Year of publication
2011
Drugs