Annotation Detail

Information
Associated Genes
MEFV
Associated Variants
MEFV p.Arg408Gln (p.R408Q) ( ENST00000536379.5, ENST00000339854.8, ENST00000219596.6, ENST00000541159.5 )
MEFV p.Pro369Ser (p.P369S) ( ENST00000219596.6, ENST00000541159.5, ENST00000339854.8, ENST00000536379.5 )
MEFV p.Pro369Thr (p.P369T) ( ENST00000536379.5, ENST00000219596.6, ENST00000339854.8, ENST00000541159.5 )
MEFV p.Arg202Gln (p.R202Q) ( ENST00000339854.8, ENST00000536379.5, ENST00000219596.6, ENST00000541159.5 )
MEFV p.Glu148Gln (p.E148Q) ( ENST00000541159.5, ENST00000339854.8, ENST00000536379.5, ENST00000219596.6 )
MEFV p.Arg408Gln (p.R408Q) ( ENST00000219596.6, ENST00000339854.8, ENST00000536379.5, ENST00000541159.5 )
MEFV p.Pro369Ser (p.P369S) ( ENST00000219596.6, ENST00000339854.8, ENST00000536379.5, ENST00000541159.5 )
MEFV p.Pro369Thr (p.P369T) ( ENST00000219596.6, ENST00000339854.8, ENST00000536379.5, ENST00000541159.5 )
MEFV p.Arg202Gln (p.R202Q) ( ENST00000219596.6, ENST00000339854.8, ENST00000536379.5, ENST00000541159.5 )
MEFV p.Glu148Gln (p.E148Q) ( ENST00000219596.6, ENST00000339854.8, ENST00000536379.5, ENST00000541159.5 )
Associated Disease
familial Mediterranean fever
Source Database
DisGeNET
Description
She was later found to carry the complex allele E148Q/R202Q/P369S/R408Q of MEFV, the gene responsible for familial Mediterranean fever.
Pubmed
23861027
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.752692202909606
Year of publication
2014
Drugs