Annotation Detail

Information
Associated Genes
MEFV
Associated Variants
MEFV p.Val726Ala (p.V726A) ( ENST00000536379.5, ENST00000541159.5, ENST00000219596.6, ENST00000339854.8 )
MEFV p.Val726Asp (p.V726D) ( ENST00000536379.5, ENST00000219596.6, ENST00000339854.8, ENST00000541159.5 )
MEFV p.Met680Ile (p.M680I) ( ENST00000541159.5, ENST00000339854.8, ENST00000219596.6, ENST00000536379.5 )
MEFV p.Met680Ile (p.M680I) ( ENST00000339854.8, ENST00000541159.5, ENST00000536379.5, ENST00000219596.6 )
MEFV p.Pro369Ser (p.P369S) ( ENST00000219596.6, ENST00000541159.5, ENST00000339854.8, ENST00000536379.5 )
MEFV p.Pro369Thr (p.P369T) ( ENST00000536379.5, ENST00000219596.6, ENST00000339854.8, ENST00000541159.5 )
MEFV p.Glu148Gln (p.E148Q) ( ENST00000541159.5, ENST00000339854.8, ENST00000536379.5, ENST00000219596.6 )
MEFV p.Val726Ala (p.V726A) ( ENST00000219596.6, ENST00000339854.8, ENST00000536379.5, ENST00000541159.5 )
MEFV p.Val726Asp (p.V726D) ( ENST00000219596.6, ENST00000339854.8, ENST00000536379.5, ENST00000541159.5 )
MEFV p.Met680Ile (p.M680I) ( ENST00000219596.6, ENST00000339854.8, ENST00000536379.5, ENST00000541159.5 )
MEFV p.Met680Ile (p.M680I) ( ENST00000219596.6, ENST00000339854.8, ENST00000536379.5, ENST00000541159.5 )
MEFV p.Pro369Ser (p.P369S) ( ENST00000219596.6, ENST00000339854.8, ENST00000536379.5, ENST00000541159.5 )
MEFV p.Pro369Thr (p.P369T) ( ENST00000219596.6, ENST00000339854.8, ENST00000536379.5, ENST00000541159.5 )
MEFV p.Glu148Gln (p.E148Q) ( ENST00000219596.6, ENST00000339854.8, ENST00000536379.5, ENST00000541159.5 )
Associated Disease
familial Mediterranean fever
Source Database
DisGeNET
Description
We screened 207 BD patients who had no symptoms and family history for FMF and 200 healthy subjects for five common MEFV gene mutations (E148Q, M680I, M694V, V726A, P369S) and clinical features.
Pubmed
23973724
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.752692202909606
Year of publication
2013
Drugs