Annotation Detail
Information
- Associated Genes
- HLA-E
- Associated Variants
-
HLA-G p.Leu159CysfsTer60 (p.L159Cfs*60)
(
ENST00000376815.3,
ENST00000360323.11,
ENST00000376818.7,
ENST00000376828.6 )
HLA-G p.Leu159CysfsTer60 (p.L159Cfs*60) ( ENST00000360323.11, ENST00000376815.3, ENST00000376818.7, ENST00000376828.6 )
HLA-E MUTATION
HLA-E MUTATION
HLA-F p.Pro71Gln (p.P71Q) ( ENST00000259951.12, ENST00000334668.8, ENST00000376861.5, ENST00000434407.6 )
HLA-F p.Pro71Gln (p.P71Q) ( ENST00000259951.12, ENST00000334668.8, ENST00000376861.5, ENST00000434407.6 ) - Associated Disease
- hepatitis B
- Source Database
- DisGeNET
- Description
- Four SNPs (rs17875380, rs41557518, rs114465251, and rs115492845) were associated with altered susceptibility to HBV or HCC, and HLA-F*01:04, HLA-G*01:05N, and HLA-E*01:01 were associated with hepatitis B or hepatitis B complicated with HCC.
- Pubmed
- 22015712
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00434306995328485
- Year of publication
- 2012
Drugs