Annotation Detail

Information
Associated Genes
SHMT1
Associated Variants
SHMT1 MUTATION
SHMT1 MUTATION
Associated Disease
Cardiovascular Diseases
Source Database
DisGeNET
Description
We identified novel associations between SNPs in CD320 and DNMT2, which had been previously associated with neural tube defects, and vitamin B-12 status, as well as between SNPs in SHMT1, which had been previously associated with colorectal cancer and cardiovascular disease risk, and RBC folate status.
Pubmed
25948668
Section of the abstract supporting the evidence
CONCLUSIONS
Number of the section of the abstract supporting the evidence
5
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.00581983144552528
Drugs