Annotation Detail

Information
Associated Genes
IL1B
Associated Variants
IL1B c.597+76G>A ( ENST00000263341.7 )
IL1B p.Phe105= (p.F105=) ( ENST00000263341.7 )
IL1B c.597+76G>A ( ENST00000263341.7 )
IL1B p.Phe105= (p.F105=) ( ENST00000263341.7 )
Associated Disease
Lung diseases
Source Database
DisGeNET
Description
SNPs rs1143634 and rs1143639 in the IL1B gene demonstrated a consistent association with lung disease severity categories (P < 0.10) and longitudinal analysis of lung disease severity (P < 0.10) in CF in both the case-control and family-based studies.
Pubmed
19431193
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0819000931045621
Year of publication
2009
Drugs