Annotation Detail

Information
Associated Genes
IL1B
Associated Variants
IL1B p.Phe105= (p.F105=) ( ENST00000263341.7 )
IL1B p.Phe105= (p.F105=) ( ENST00000263341.7 )
Associated Disease
Malignant neoplasm of prostate
Source Database
DisGeNET
Description
[Using Multivariate Adaptive Regression Splines modeling for exploratory SNP-SNP interactions, our results showed that more aggressive PCa in Caucasians Americans is associated with the CT genotype at IL8-47 odds ratios (OR) = 3.50; 95% CI = 1.13-10.88 or combined genotypes of IL1B-511CC and IL10-1082GG (OR = 3.38; 95% CI = 1.70-6.71).]
Pubmed
19474090
Original source reporting the Gene Disease association
GAD
DisGENET score for the Gene Disease association
0.0177309362086561
Year of publication
2009
Drugs