Annotation Detail
Information
- Associated Genes
- IL1RN
- Associated Variants
-
rs1800587
IL1B SNV
IL1B p.Phe105= (p.F105=) ( ENST00000263341.7 )
NC_000002.12:g.112837290A>G
rs1800587
IL1B SNV
IL1B p.Phe105= (p.F105=) ( ENST00000263341.7 )
NC_000002.12:g.112837290A>G - Associated Disease
- Degenerative polyarthritis
- Source Database
- DisGeNET
- Description
- Haplotype analyses revealed gender disparities and showed that women carriers of the 1-2-1-1 haplotype [IL-1A(rs1800587) - IL-1B(rs1143634) - IL-1B(rs16944) - IL-1RN(VNTR)] had sixfold lower risk to develop knee OA.
- Pubmed
- 23216199
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0258081790226087
- Year of publication
- 2013
Drugs