Annotation Detail

Information
Associated Genes
POLG
Associated Variants
POLG p.Trp748Ser (p.W748S) ( ENST00000442287.6, ENST00000636937.2, ENST00000268124.11 )
POLG p.Trp748Ser (p.W748S) ( ENST00000268124.11, ENST00000442287.6, ENST00000636937.2 )
Associated Disease
Mitochondrial Diseases
Source Database
DisGeNET
Description
Mitochondrial disorder was clinically suspected and a homozygous c.2243G>C mutation (p.Trp748Ser) was discovered in the POLG1 gene.
Pubmed
23248042
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.255763491623986
Year of publication
2012
Drugs