Annotation Detail

Information
Associated Genes
POLG
Associated Variants
POLG p.Pro587Leu (p.P587L) ( ENST00000442287.6, ENST00000636937.2, ENST00000268124.11 )
POLG p.Pro587Leu (p.P587L) ( ENST00000268124.11, ENST00000442287.6, ENST00000636937.2 )
Associated Disease
Alpers Syndrome (disorder)
Source Database
DisGeNET
Description
Novel POLG mutations in progressive external ophthalmoplegia mimicking mitochondrial neurogastrointestinal encephalomyopathy.
Pubmed
12825077
Original source reporting the Gene Disease association
UNIPROT
DisGENET score for the Gene Disease association
0.48868613990657
Year of publication
2003
Drugs