Annotation Detail

Information
Associated Genes
CFTR
Associated Variants
CFTR p.Gly542Ter (p.G542*) ( ENST00000003084.11, ENST00000648260.1, ENST00000649406.1, ENST00000649781.2, ENST00000699602.1, ENST00000699605.1 )
CFTR p.Gly542Ter (p.G542*) ( ENST00000003084.11, ENST00000648260.1, ENST00000649406.1, ENST00000649781.2, ENST00000699602.1, ENST00000699605.1 )
Associated Disease
cystic fibrosis
Source Database
DisGeNET
Description
Poly-L-aspartic acid enhances and prolongs gentamicin-mediated suppression of the CFTR-G542X mutation in a cystic fibrosis mouse model.
Pubmed
19136563
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.8
Year of publication
2009
Drugs