Annotation Detail

Information
Associated Genes
PHF3 EYS
Associated Variants
EYS p.Ile3091Thr (p.I3091T), PHF3 c.*7114A>G ( ENST00000370621.7, ENST00000503581.6, ENST00000262043.8 )
EYS p.Ile3091Thr (p.I3091T), PHF3 c.*7114A>G ( ENST00000262043.8, ENST00000370621.7, ENST00000503581.6 )
Associated Disease
Retinal dystrophy
Source Database
ClinVar
Description
NM_001142800.2(EYS):c.9209T>C (p.Ile3070Thr) AND Retinal dystrophy
ClinVar Disease
Retinal dystrophy
Observed Origin Sample
germline
ClinVar Allele ID
152834
ClinVar RefSeq Alternation Syntax
NM_015153.4:c.*7114A>G
ClinVar RefSeq Alternation Syntax
NM_001370348.2:c.*7114A>G
ClinVar RefSeq Alternation Syntax
NM_001292009.2:c.9272T>C
ClinVar RefSeq Alternation Syntax
NM_001142800.2:c.9209T>C
ClinVar RefSeq Alternation Syntax
NM_001370350.2:c.*7114A>G
ClinVar RefSeq Alternation Syntax
NM_001290259.2:c.*7114A>G
ClinVar RefSeq Alternation Syntax
NM_001370349.2:c.*7114A>G
Clinical Significance Description
Likely benign
Clinical Significance Last Update
2023-10-01
Clinical Significance Review Status
criteria provided, single submitter
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV003888558
Drugs