Annotation Detail

Information
Associated Genes
MAP2K1
Associated Variants
MAP2K1 p.Gln56_Val60del (p.Q56_V60del) ( ENST00000685172.1, ENST00000692683.1, ENST00000685763.1, ENST00000693150.1, ENST00000307102.10, ENST00000689951.1, ENST00000691937.1, ENST00000686347.1, ENST00000691576.1 )
MAP2K1 p.Gln56_Val60del (p.Q56_V60del) ( ENST00000307102.10, ENST00000685172.1, ENST00000685763.1, ENST00000686347.1, ENST00000689951.1, ENST00000691576.1, ENST00000691937.1, ENST00000692683.1, ENST00000693150.1 )
Associated Disease
Vascular malformation
Source Database
ClinVar
Description
NM_002755.4(MAP2K1):c.165_179del (p.Gln56_Val60del) AND Vascular malformation
ClinVar Allele ID
2839619
ClinVar RefSeq Alternation Syntax
NM_001411065.1:c.99_113del
ClinVar RefSeq Alternation Syntax
NM_002755.4:c.165_179del
Clinical Significance Description
Likely pathogenic
Clinical Significance Last Update
2023-09-11
Clinical Significance Review Status
criteria provided, single submitter
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV003458961
ClinVar Disease
Vascular malformation
Observed Origin Sample
somatic
Drugs