Annotation Detail

Information
Associated Genes
AIRE
Associated Variants
AIRE p.Arg139Gly (p.R139G) ( ENST00000291582.6 )
AIRE p.Arg139Gly (p.R139G) ( ENST00000291582.6 )
Associated Disease
Polyglandular autoimmune syndrome, type 1
Source Database
ClinVar
Description
NM_000383.4(AIRE):c.415C>G (p.Arg139Gly) AND Polyglandular autoimmune syndrome, type 1
ClinVar Allele ID
2128951
ClinVar RefSeq Alternation Syntax
NM_000383.4:c.415C>G
Clinical Significance Description
Likely benign
Clinical Significance Last Update
2023-11-25
Clinical Significance Review Status
criteria provided, single submitter
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV002933996
ClinVar Disease
Polyglandular autoimmune syndrome, type 1
Observed Origin Sample
germline
Drugs