Annotation Detail

Information
Associated Genes
TGFBI
Associated Variants
TGFBI p.Arg124Ser (p.R124S) ( ENST00000442011.7 )
TGFBI p.Arg124Ser (p.R124S) ( ENST00000442011.7 )
Associated Disease
epithelial-stromal TGFBI dystrophy
Source Database
ClinVar
Description
NM_000358.3(TGFBI):c.370C>A (p.Arg124Ser) AND Epithelial-stromal TGFBI dystrophy
ClinVar Allele ID
22912
ClinVar RefSeq Alternation Syntax
NM_000358.3:c.370C>A
Clinical Significance Description
Pathogenic
Clinical Significance Last Update
2021-09-21
Clinical Significance Review Status
criteria provided, single submitter
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV002466396
ClinVar Disease
Epithelial-stromal TGFBI dystrophy
Observed Origin Sample
germline
Drugs