Annotation Detail
Information
- Associated Genes
- KRAS
- Associated Variants
-
KRAS p.Gly12Val (p.G12V)
(
ENST00000688940.1,
ENST00000692768.1,
ENST00000256078.10,
ENST00000311936.8,
ENST00000556131.2,
ENST00000557334.6,
ENST00000685328.1,
ENST00000686969.1,
ENST00000693229.1 )
KRAS p.Gly12Val (p.G12V) ( ENST00000693229.1, ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1 ) - Associated Disease
- chronic myelogenous leukemia, BCR-ABL1 positive
- Source Database
- ClinVar
- Description
- NM_004985.5(KRAS):c.35G>T (p.Gly12Val) AND Chronic myelogenous leukemia, BCR-ABL1 positive
- ClinVar Allele ID
- 27622
- ClinVar RefSeq Alternation Syntax
- NM_001369786.1:c.35G>T
- ClinVar RefSeq Alternation Syntax
- NM_001369787.1:c.35G>T
- ClinVar RefSeq Alternation Syntax
- NM_033360.4:c.35G>T
- ClinVar RefSeq Alternation Syntax
- NM_004985.5:c.35G>T
- Clinical Significance Description
- Pathogenic
- Clinical Significance Last Update
- 2022-10-10
- Clinical Significance Review Status
- no assertion criteria provided
- URL
- https://www.ncbi.nlm.nih.gov/clinvar/RCV002291496
- ClinVar Disease
- Chronic myelogenous leukemia, BCR-ABL1 positive
- Observed Origin Sample
- somatic
Drugs