Annotation Detail

Information
Associated Genes
TGFBI
Associated Variants
TGFBI p.Arg555Trp (p.R555W) ( ENST00000442011.7 )
TGFBI p.Arg555Trp (p.R555W) ( ENST00000442011.7 )
Associated Disease
Lattice corneal dystrophy Type I
Source Database
ClinVar
Description
NM_000358.3(TGFBI):c.1663C>T (p.Arg555Trp) AND Lattice corneal dystrophy Type I
ClinVar Allele ID
22905
ClinVar RefSeq Alternation Syntax
NM_000358.3:c.1663C>T
Clinical Significance Description
Pathogenic
Clinical Significance Last Update
2022-05-03
Clinical Significance Review Status
criteria provided, single submitter
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV002288474
ClinVar Disease
Lattice corneal dystrophy Type I
Observed Origin Sample
germline
Drugs