Annotation Detail

Information
Associated Genes
GALT
Associated Variants
GALT p.Thr138Met (p.T138M) ( ENST00000378842.8, ENST00000450095.6 )
GALT p.Val157Ile (p.V157I) ( ENST00000378842.8, ENST00000450095.6 )
GALT p.Thr138Met (p.T138M) ( ENST00000378842.8, ENST00000450095.6 )
GALT p.Val157Ile (p.V157I) ( ENST00000378842.8, ENST00000450095.6 )
Associated Disease
Deficiency of UDPglucose-hexose-1-phosphate uridylyltransferase
Source Database
ClinVar
Description
NM_000155.4(GALT):c.[413C>T;469G>A] AND Deficiency of UDPglucose-hexose-1-phosphate uridylyltransferase
ClinVar Allele ID
36508
ClinVar Allele ID
1152415
ClinVar RefSeq Alternation Syntax
NM_000155.4:c.413C>T
ClinVar RefSeq Alternation Syntax
NM_001258332.2:c.86C>T
ClinVar RefSeq Alternation Syntax
NM_000155.4:c.469G>A
ClinVar RefSeq Alternation Syntax
NM_001258332.2:c.142G>A
Clinical Significance Description
Pathogenic
Clinical Significance Last Update
2022-08-19
Clinical Significance Review Status
criteria provided, single submitter
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV002281776
ClinVar Disease
Deficiency of UDPglucose-hexose-1-phosphate uridylyltransferase
Observed Origin Sample
germline
Drugs