Annotation Detail

Information
Associated Genes
XRCC4
Associated Variants
XRCC4 p.Ser309= (p.S309=) ( ENST00000282268.7, ENST00000338635.10, ENST00000396027.9, ENST00000511817.1 )
XRCC4 p.Ser309= (p.S309=) ( ENST00000282268.7, ENST00000338635.10, ENST00000396027.9, ENST00000511817.1 )
Associated Disease
Short stature, microcephaly, and endocrine dysfunction
Source Database
ClinVar
Description
NM_003401.5(XRCC4):c.921T>G (p.Ser307=) AND Short stature, microcephaly, and endocrine dysfunction
ClinVar Allele ID
1236313
ClinVar RefSeq Alternation Syntax
NM_022550.4:c.921T>G
ClinVar RefSeq Alternation Syntax
NM_003401.5:c.921T>G
ClinVar RefSeq Alternation Syntax
NM_022406.5:c.927T>G
ClinVar RefSeq Alternation Syntax
NM_001318012.3:c.927T>G
Clinical Significance Description
Benign
Clinical Significance Last Update
2021-12-05
Clinical Significance Review Status
criteria provided, single submitter
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV002243357
ClinVar Disease
Short stature, microcephaly, and endocrine dysfunction
Observed Origin Sample
germline
Drugs