Annotation Detail
Information
- Associated Genes
- TNFRSF1B
- Associated Variants
-
TNFRSF1B p.Met196Arg (p.M196R)
(
ENST00000376259.7 )
TNFRSF1B p.Met196Arg (p.M196R) ( ENST00000376259.7 ) - Associated Disease
- Susceptibility to severe coronavirus disease (COVID-19) due to high plasma levels of TNF, TNFR, and/or TNFR2
- Source Database
- ClinVar
- Description
- NM_001066.3(TNFRSF1B):c.587T>G (p.Met196Arg) AND Susceptibility to severe coronavirus disease (COVID-19) due to high plasma levels of TNF, TNFR, and/or TNFR2
- ClinVar Allele ID
- 1036917
- ClinVar RefSeq Alternation Syntax
- NM_001066.3:c.587T>G
- Clinical Significance Description
- Uncertain significance
- Clinical Significance Last Update
- 2021-08-07
- Clinical Significance Review Status
- no assertion criteria provided
- URL
- https://www.ncbi.nlm.nih.gov/clinvar/RCV001836993
- ClinVar Disease
- Susceptibility to severe coronavirus disease (COVID-19) due to high plasma levels of TNF, TNFR, and/or TNFR2
- Observed Origin Sample
- germline
Drugs